研究業績

2016年

Saiga R, Mizutani R, Inomoto C, Takekoshi S, Nakamura N, Tsuboi A, Motoki O, Arai M, Oshima K, Itokawa M, Uesugi K, Takeuchi A, Terada Y, Suzuki Y. Three-Dimensional Structure of Brain Tissue at Submicrometer Resolution. AIP Conference Proceedings. 1696, 020004 (2016); http://dx.doi.org/10.1063/1.4937498

2015年

Mizutani R, Saiga R, Takekoshi S, Arai M, Takeuchi A, Suzuki Y. Scanning Brain Networks with Micro-CT. 2015 23(5):12-17

Saiga R, Takekoshi S, Inomoto C, Nakamura N, Tsuboi A, Osawa M, Arai M, Oshima K, Itokawa M, Uesugi K, Takeuchi A, Terada Y, Suzuki Y, Mizutani R. Three-Dimensional Neuronal Structure of Human Cerebral Cortex Determined by Synchrotron-Radiation Microtomography. 2015 21(3) 919-920

Mizutani R, Saiga R, Takekoshi S, Inomoto C, Nakamura N, Itokawa M, Arai M, Oshima K, Takeuchi A, Uesugi K, Terada Y, Suzuki Y. A method for estimating spatial resolution of real image in the Fourier domain. J Microsc. 2015 Jan;261(1):57-66.

Matsuzaki T, Takekoshi S, Toriumi K, Kitatani K, Nitou M, Imamura N, Ogura G, Masuda R, Nakamura N, Iwazaki M. Reduced Expression of Hugl 1 Contributes to the Progression of Lung Squamous Cell Carcinoma. Tokai J Exp Clin Med. 2015 Dec 20;40(4):169-177.

Horikoshi Y, Kitatani K, Toriumi K, Fukunishi N, Itoh Y, Nakamura N, Ohno S, Matsura T, Takekoshi S. Aberrant Activation of Atypical Protein Kinase C in Carbon Tetrachloride-Induced Oxidative Stress Provokes a Disturbance of Cell Polarity and Sealing of Bile Canalicular Lumen. American Journal of Pathology. 2015 85 (4) : 958-968

2014

Kawabata K, Kobayashi M, Kusaka-Kikushima A, Akasaka E, Mabuchi T, Fukui T, Sugiyama Y, Takekoshi S, Miyasaka M, Ozawa A, Sakai S. A new objective histological scale for studying human photoaged skin. Skin Res Technol. 2014 ; 20:155-163

Goto Y1, Kametani Y, Kikugawa A, Tsuda B, Miyazawa M, Kajiwara H, Terao Y, Takekoshi S, Nakamura N, Takeda S, Mikami M. Defect of tropomyosin-related kinase B isotype expression in ovarian clear cell adenocarcinoma. Biosci Trends. 2014 Apr;8(2):93-100.

Kawaguchi AT1, Okamoto Y, Kise Y, Takekoshi S, Murayama C, Makuuchi H. Effects of Liposome-Encapsulated Hemoglobin on Gastric Wound Healing in the Rat. Artif Organs. 2014 Jun 12.doi: 10.1111/aor.12339.

Takekoshi S, Yasui Y, Inomoto C, Kitatani K, Nakamura N, Osamura Y. A histopathological study of multi-hormone producing proliferative lesions in estrogen-induced rat pituitary prolactinoma. Acta Histochemca Cytochemica 2014 Aug 29;47(4):155-64

Takekoshi S, Nagata H, Kitatani K. Flavonoids enhance melanogenesis in human melanoma cells. Tokai J Exp Med. 2014 Sep 20;39(3):116-21

Takekoshi S, Kitatani K, Yamamoto Y. Roles of oxidized diacylglycerol for carbon tetrachloride-induced liver injury and fibrosis in mouse. Acta Histochemca Cytochemica 2014 47 (5): 185–194

Ota T, Takekoshi S, Takagi T, Kitatani K, Toriumi K, Kojima T, Kato M, Ikoma N, Mabuchi T, Ozawa A. Notch signaling may be involved in the abnormal differentiation of epidermal keratinocytes in psoriasis. Acta Histochemca Cytochemica 2014 47 (4): 175–183

Takekoshi S, Nagata H, Kitatani K. Stimulation of melanogenesis by nordihydroguaiaretic acid in human melanoma cells. Acta Histochemca Cytochemica 2014 47 (5): 203–210

2013

Toriumi K, Horikoshi Y, Yoshiyuki Osamura R, Yamamoto Y, Nakamura N, Takekoshi S. Carbon tetrachloride-induced hepatic injury through formation of oxidized diacylglycerol and activation of the PKC/NF-κB pathway. Lab Invest. 2013 93:218-29

Kikuchi T, Tokunaka M, Kikuti YY, Carreras J, Ogura G, Takekoshi S, Kojima M, Ando K, Hashimoto Y, Abe M, Takata K, Yoshino T, Muto A, Igarashi K, Nakamura N. Over-expression of BACH2 is related to ongoing somatic hypermutation of the immunoglobulin heavy chain gene variable region of de novo diffuse large B-cell lymphoma. Pathol Int. 2013 Jul;63(7):339-44

Takekoshi S, Matsuzaki K, Kitatani K. Quercetin stimulates melanogenesis in hair follicle melanocyte of the mouse. Tokai J Exp Clin Med. 2013 Dec 20;38(4):129-34.

Imamura N, Horikoshi Y, Matsuzaki T, Toriumi K, Kitatani K, Ogura G, Masuda R, Nakamura N, Takekoshi S, Iwazaki M. Localization of aPKC Lambda/Iota and Its Interacting Protein, Lgl2, Is Significantly Associated with Lung Adenocarcinoma Progression. Tokai J Exp Clin Med. 2013 Dec 20;38(4):146-58.

2012

Tsuyoshi Fukui, Akira T. Kawaguchi, Susumu Takekoshi, Muneo Miyasaka, Rica Tanaka. Liposome-Encapsulated Hemoglobin Accelerates Skin Wound Healing in Mice. Artificial Organs 36:161-169:2012

Deepak Chhabra, Koji Oda, Palepu Jagannath1, Hirotoshi Utsunomiya, Susumu Takekoshi, Yuji Nimura. Chronic Heavy Metal Exposure and Gallbladder Cancer Risk in India, a Comparative Study with Japan. Asian Pac J Cancer Prev. 2012:13:187-90

Sugiyama T, Miyazawa M, Mikami M, Goto Y, Nishijima Y, Ikeda M, Hirasawa T, Muramatsu T, Takekoshi S, Iwamori M. Enhanced expression of sulfatide, a sulfated glycolipid, in well-differentiated endometrial adenocarcinoma. Int J Gynecol Cancer. 2012 :22:1192-7

Masuda S, Kadowaki T, Kumaki N, Tang X, Tokuda Y, Yoshimura S, Takekoshi S, Osamura RY. Analysis of gene alterations of mitochondrial DNA D-loop regions to determine breast cancer clonality. Br J Cancer. 2012 Dec 4;107(12):2016-2

2011

Noboru Egashira, Susumu Takekoshi, Mao Takei, Akira Teramoto and Robert Yoshiyuki Osamura Expression of FOXL2 in Human Normal Pituitaries and Pituitary Adenomas. Modern Pathology 2011:24:765-773

Kana Tajima, Yoshiaki Kawaguchi, Hiroyuki Ito, Masami Ogawa, Kentaro Toriumi, Kenichi Hirabayashi, Susumu Takekoshi, Tetsuya Mine. A case of pancreatic solid-pseudopapillary neoplasm with marked ossification. Clin J Gastroenterol 2011:4:112-117

Harasawa M, Yasuda M, Hirasawa T, Miyazawa M, Shida M, Muramatsu T, Douguchi K, Matsui N, Takekoshi S, Kajiwara H, Yoshiyuki Osamura R, Mikami M. Analysis of mTOR inhibition-involved pathway in ovarian clear cell adenocarcinoma. Acta Histochemca Cytochemica 2011:44:113-118

Matsuno A, Mizutani A, Okinaga H, Takano K, Yamada S, Yamada SM, Nakaguchi H, Hoya K, Murakami M, Takeuchi M, Sugaya M, Itoh J, Takekoshi S, Osamura RY. Molecular morphology of pituitary cells, from conventional immunohistochemistry to fluorescein imaging. Molecules 2011:16:3618-3635

Matsuno A, Mizutani A, Okinaga H, Takano K, Yamada S, Yamada SM, Nakaguchi H, Hoya K, Murakami M, Takeuchi M, Sugaya M, Itoh J, Takekoshi S, Osamura RY. Functional molecular morphology of anterior pituitary cells, from hormone production to intracellular transport and secretion. Med Mol Morphol 2011:44:63-70

Taniguchi Y, Tanaka O, Sekiguchi M, Takekoshi S, Tsukamoto H, Kimura M, Imai K, Inoko H. Enforced expression of the transcription factor HOXD3 under the control of the Wnt1 regulatory element modulates cell adhesion properties in the developing mouse neural tube. J Anat. 2011:219:589-600

Ishino H, Hara Y, Takekoshi S, Teshima T, Teramoto A, Osamura RY, Tagawa M. Ki-67 and minichromosome maintenance-7 (MCM7) expression in canine pituitary corticotroph adenomas. Domest Anim Endocrinol. 2011:14:207-213

Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Susumu Takekoshi, Naoya Nakamura, Yoshio Suzuki. Building human brain network in 3D coefficient map determined by X-ray microtomography. AIP Conf. Ser. 2011:1365:403-406